Across TCGA pan-cancer cohorts, KIF2B RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KIF2B’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where KIF2B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIF2B is over-expressed in tumor.
UCEC and HNSC are the cancer types where KIF2B tumor–normal differential expression is most reproducible.