KIF27

Across TCGA patient cohorts, KIF27 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,852 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF27-associated proteins across cancer lineages are THEMIS2, PLCG2, and BRD3. Each is linked with KIF27 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF27-to-partner and partner-to-KIF27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF27 versus THEMIS2 in GBM, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF27→partner) and Y-score (partner→KIF27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THEMIS2 →	-0.450	-0.394	.002	.009	3	5
UCEC	PLCG2 →	-0.620	-0.763	<.001	<.001	3	5
GBM	BRD3 →	+0.334	+0.398	<.001	<.001	3	5
BRCA	CALR →	-0.385	-0.630	<.001	<.001	3	5
OV	CETN2 →	+0.370	+0.590	.005	.003	2	6
GBM	DOK3 →	-0.470	-0.430	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,852 associations by consensus.

KIF27 vs THEMIS2 — GBM

Explore this scatter interactively →