KIF27

Across TCGA patient cohorts, KIF27 protein abundance is significantly associated with the RNA expression of many other genes, with 2,390 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF27-associated genes across cancer lineages are PPM1B, LGALS7B, and SPAST. Each is linked with KIF27 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF27-to-partner and partner-to-KIF27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF27 versus PPM1B in BRCA, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF27→partner) and Y-score (partner→KIF27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPM1B →	-0.503	-0.663	.002	.009	3	2
LSCC	LGALS7B →	-2.106	-0.436	.005	<.001	3	2
BRCA	SPAST →	-0.346	-0.467	.004	.007	3	2
UCEC	C2orf16 →	-0.627	-0.438	.004	.002	3	2
LUAD	SRP14P4 →	-0.989	-0.333	.002	.002	3	2
LUAD	HAMP →	+0.702	+0.397	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,390 associations by consensus.

KIF27 vs PPM1B — BRCA

Explore this scatter interactively →