KIF27

Across TCGA patient cohorts, KIF27 mutation is significantly associated with the RNA expression of many other genes, with 3,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF27-associated genes across cancer lineages are UBAC1, PSMB7, and VTRNA2-2P. Each is linked with KIF27 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF27-to-partner and partner-to-KIF27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBAC1 grouped by KIF27-low versus KIF27-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF27→partner) and Y-score (partner→KIF27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBAC1 →	+0.251	+1.465	.005	.001	3	4
UCEC	PSMB7 →	+0.282	+2.621	<.001	<.001	3	4
CESC	VTRNA2-2P →	+0.579	+4.601	<.001	.004	3	3
CESC	FRG2GP →	+0.050	+4.539	.008	.008	3	3
LGG	AGGF1P4 →	+0.054	+7.977	<.001	.007	3	3
STAD	DHPS →	+0.378	+3.338	.005	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,053 associations by consensus.

UBAC1 by KIF27 expression — UCEC

Explore this box plot interactively →