KIF27

Across TCGA cell cohorts, KIF27 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,079 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF27-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with KIF27 in more than 15 cancer types. Because this analysis shows association rather than direction, both KIF27-to-partner and partner-to-KIF27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by KIF27-low versus KIF27-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF27→partner) and Y-score (partner→KIF27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.125	+0.719	<.001	<.001	3	16
OVARY	Negative regulation of myoblast fusion →	+0.133	+0.673	<.001	<.001	3	16
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.132	+0.673	<.001	<.001	3	16
URINARY_TRACT	Regulation of organelle assembly →	+0.055	+0.811	<.001	<.001	3	16
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.121	+0.705	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.124	-0.660	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,079 associations by consensus.

Regulation of myoblast fusion by KIF27 expression — OVARY

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