KIF26A

Across TCGA patient cohorts, KIF26A mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF26A-associated genes across cancer lineages are FOXO3a_pS318_S321, GAPDH, and Lck. Each is linked with KIF26A in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF26A-to-partner and partner-to-KIF26A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a_pS318_S321 grouped by KIF26A-low versus KIF26A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF26A→partner) and Y-score (partner→KIF26A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.150	-1.847	.001	.008	3	3
COAD	GAPDH →	+0.497	+2.182	.029	.033	3	3
UCEC	Lck →	+0.230	+2.115	.001	.017	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.395	-1.584	.016	.034	3	2
UCEC	Rictor_pT1135 →	-0.105	-2.906	.005	.001	3	2
UCEC	ATM →	-0.389	-3.308	.019	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

FOXO3a_pS318_S321 by KIF26A expression — UCEC

Explore this box plot interactively →