Across TCGA patient cohorts, KIF25 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,133 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible KIF25-associated GO terms across cancer lineages are Chaperone-mediated protein folding, Positive regulation of DNA repair, and Positive regulation of DNA biosynthetic process. Each is linked with KIF25 in more than 16 cancer types. Because this analysis shows association rather than direction, both KIF25-to-partner and partner-to-KIF25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF25→partner) and Y-score (partner→KIF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Chaperone-mediated protein folding →	+0.049	+0.120	<.001	<.001	3	16
STAD	Positive regulation of DNA repair →	+0.041	+0.136	<.001	<.001	3	16
ESCA	Positive regulation of DNA biosynthetic process →	+0.060	+0.515	<.001	<.001	3	16
ESCA	U2-type prespliceosome assembly →	+0.075	+0.461	<.001	<.001	3	16
ESCA	NADH dehydrogenase complex assembly →	+0.053	+0.389	.002	.002	3	15
STAD	Obsolete histone methylation →	+0.072	+0.201	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,133 associations by consensus.

Exploration

KIF25 survival (RNA) · tumor vs normal (RNA) · all KIF25 data types