KIF25

Across TCGA patient cohorts, KIF25 protein abundance is significantly associated with the RNA expression of many other genes, with 6,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF25-associated genes across cancer lineages are ZBP1, SFRP2, and DOK3. Each is linked with KIF25 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF25-to-partner and partner-to-KIF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF25 versus ZBP1 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF25→partner) and Y-score (partner→KIF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZBP1 →	+0.794	+0.556	<.001	<.001	3	2
BRCA	SFRP2 →	+1.961	+0.703	.004	.006	2	3
LUAD	DOK3 →	+0.616	+0.770	.002	.001	3	2
LUAD	FNDC1 →	+1.185	+0.990	.001	<.001	3	2
LSCC	SF3B5 →	-0.581	-0.761	<.001	<.001	3	2
LSCC	PTRHD1 →	-0.438	-0.585	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,704 associations by consensus.

KIF25 vs ZBP1 — LSCC

Explore this scatter interactively →