KIF25

Across TCGA patient cohorts, KIF25 mutation is significantly associated with the RNA expression of many other genes, with 2,558 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF25-associated genes across cancer lineages are MIR7843, HSBP1P2, and RNU6-98P. Each is linked with KIF25 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF25-to-partner and partner-to-KIF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7843 grouped by KIF25-low versus KIF25-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF25→partner) and Y-score (partner→KIF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR7843 →	+0.376	+4.091	<.001	.002	3	2
CESC	HSBP1P2 →	+0.159	+3.106	<.001	.007	3	2
CESC	RNU6-98P →	+0.143	+4.020	<.001	.009	3	2
CESC	SNORA36A →	+0.204	+3.483	.002	.002	3	2
CESC	MIR7-3 →	+0.152	+4.020	<.001	.009	3	2
CESC	RNU6-1139P →	+0.165	+5.263	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,558 associations by consensus.

MIR7843 by KIF25 expression — BRCA

Explore this box plot interactively →