KIF25

Across TCGA cell cohorts, KIF25 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,916 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KIF25-associated GO terms across cancer lineages are Regulation of protein localization to Cajal body, Positive regulation of protein localization to Cajal body, and Regulation of RNA splicing. Each is linked with KIF25 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF25-to-partner and partner-to-KIF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to Cajal body grouped by KIF25-low versus KIF25-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF25→partner) and Y-score (partner→KIF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein localization to Cajal body →	+0.054	+0.223	.004	.009	3	6
BREAST	Positive regulation of protein localization to Cajal body →	+0.054	+0.223	.004	.009	3	6
SOFT_TISSUE	Regulation of RNA splicing →	+0.071	+0.397	<.001	.002	3	6
BREAST	Negative regulation of mRNA splicing, via spliceosome →	+0.097	+0.242	<.001	<.001	3	6
PANCREAS	Regulation of mRNA processing →	+0.057	+0.337	.001	.009	3	6
BREAST	Protein-DNA complex organization →	+0.044	+0.336	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,916 associations by consensus.

Regulation of protein localization to Cajal body by KIF25 expression — BREAST

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