Across TCGA pan-cancer cohorts, KIF24 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KIF24 data layer compared with 30 for mass-spec protein and 2 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KIF24 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIF24 expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.
ACC, LUAD, and PAAD are the cancer types where KIF24 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.