Across TCGA patient cohorts, KIF24 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF24-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and 14-3-3_beta. Each is linked with KIF24 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF24-to-partner and partner-to-KIF24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF24→partner) and Y-score (partner→KIF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.435	-3.687	.005	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.804	+2.700	<.001	.005	3	2
UCEC	14-3-3_beta →	-0.107	-2.388	.002	.002	3	1
UCEC	EGFR_pY1068 →	-0.190	-1.440	.029	.024	3	1
UCEC	ERK2 →	+0.154	+2.459	.021	.018	3	1
UCEC	GATA6 →	-0.139	-3.155	.009	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

KIF24 survival (RNA) · tumor vs normal (RNA) · all KIF24 data types