Across TCGA cell cohorts, KIF24 mutation is significantly associated with the RNA expression of many other genes, with 454 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF24-associated genes across cancer lineages are MAGEB4, UNC93A, and MYH6. Each is linked with KIF24 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF24-to-partner and partner-to-KIF24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF24→partner) and Y-score (partner→KIF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.192	<.001	.002	3	2
BLOOD_Leukemia	UNC93A →	+0.115	+2.681	<.001	.008	3	2
PANCREAS	MYH6 →	+0.006	+5.000	<.001	.006	3	1
URINARY_TRACT	NEUROG3 →	+0.005	+4.087	<.001	.009	3	1
URINARY_TRACT	HORMAD2 →	+0.006	+4.217	<.001	.005	3	1
URINARY_TRACT	C16orf90 →	+0.017	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 454 associations by consensus.

Exploration

KIF24 survival (RNA) · tumor vs normal (RNA) · all KIF24 data types