Across TCGA cell cohorts, KIF24 mutation is significantly associated with the mutation status of many other genes, with 4,525 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF24-associated genes across cancer lineages are TDRD12, PHOX2B, and FRAS1. Each is linked with KIF24 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF24-to-partner and partner-to-KIF24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF24→partner) and Y-score (partner→KIF24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TDRD12 →	+4.209	+3.285	<.001	<.001	1	6
PANCREAS	PHOX2B →	+5.115	+5.115	.005	.005	1	5
LARGE_INTESTINE	FRAS1 →	+2.471	+4.700	<.001	<.001	1	5
BREAST	PPFIA3 →	+3.925	+4.974	<.001	<.001	1	5
BREAST	DNAH2 →	+3.510	+4.754	<.001	<.001	1	5
BLOOD_Leukemia	KALRN →	+2.039	+2.899	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,525 associations by consensus.

Exploration

KIF24 survival (RNA) · tumor vs normal (RNA) · all KIF24 data types