KIF23

Across TCGA pan-cancer cohorts, KIF23 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KIF23 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher KIF23 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KIF23 expression acts as an unfavorable survival marker.

PDAC, HNSC, and LUAD are the cancer types where KIF23 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.417	0.676	<.001	87	view →
HNSC	OS	Median	All	0.380	1.000	.008	30	view →
LUAD	DFS	Quartile	All	0.450	1.000	.002	20	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KIF23–PDAC (OS)

Open the PDAC breakdown →