KIF23

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF23 protein abundance is significantly associated with the RNA expression of many other genes, with 17,819 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF23-associated genes across cancer lineages are MCM5, CDKN3, and MYBL2. Each is linked with KIF23 in more than 8 cancer types. Because this analysis shows association rather than direction, both KIF23-to-partner and partner-to-KIF23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF23 versus MCM5 in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF23→partner) and Y-score (partner→KIF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMCM5 →+0.678+0.635<.001<.00139
OVCDKN3 →+1.404+0.820<.001<.00139
LUADMYBL2 →+1.822+0.920<.001<.00139
LUADE2F1 →+1.246+0.901<.001<.00139
LSCCMCM4 →+0.977+0.580<.001<.00139
BRCAASF1B →+1.005+0.444<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,819 associations by consensus.

KIF23 vs MCM5 — GBM

Per-sample scatter of KIF23 vs MCM5 in GBM (Pearson r = 0.56).

Explore this scatter interactively →

Exploration