KIF23

Across TCGA cell cohorts, KIF23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,413 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF23-associated GO terms across cancer lineages are Regulation of nuclear division, Negative regulation of nuclear division, and Mitotic sister chromatid segregation. Each is linked with KIF23 in more than 19 cancer types. Because this analysis shows association rather than direction, both KIF23-to-partner and partner-to-KIF23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear division grouped by KIF23-low versus KIF23-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF23→partner) and Y-score (partner→KIF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nuclear division →	+0.167	+1.262	<.001	<.001	3	20
BREAST	Negative regulation of nuclear division →	+0.171	+1.259	<.001	<.001	3	20
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.161	+1.231	<.001	<.001	3	20
OESOPHAGUS	Chromosome segregation →	+0.146	+1.079	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Mitotic metaphase chromosome alignment →	+0.114	+1.179	.001	.002	3	20
BREAST	Mitotic spindle assembly checkpoint signaling →	+0.183	+1.396	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,413 associations by consensus.

Regulation of nuclear division by KIF23 expression — OESOPHAGUS

Explore this box plot interactively →