KIF22

Across TCGA patient cohorts, KIF22 protein abundance is significantly associated with the RNA expression of many other genes, with 18,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF22-associated genes across cancer lineages are CDKN3, NCAPD2, and EZH2. Each is linked with KIF22 in more than 7 cancer types. Because this analysis shows association rather than direction, both KIF22-to-partner and partner-to-KIF22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF22 versus CDKN3 in LUAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF22→partner) and Y-score (partner→KIF22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDKN3 →	+1.282	+0.564	<.001	<.001	3	8
UCEC	NCAPD2 →	+0.959	+0.732	<.001	<.001	3	8
GBM	EZH2 →	+0.916	+0.524	.001	<.001	3	8
LUAD	NCAPG →	+1.293	+0.645	<.001	<.001	3	8
OV	FOXM1 →	+1.491	+0.646	<.001	<.001	3	8
BRCA	CDCA3 →	+1.120	+0.517	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,839 associations by consensus.

KIF22 vs CDKN3 — LUAD

Explore this scatter interactively →