KIF21A

Across TCGA patient cohorts, KIF21A protein abundance is significantly associated with the RNA expression of many other genes, with 14,056 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF21A-associated genes across cancer lineages are SSPN, FCGR2A, and COLEC12. Each is linked with KIF21A in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF21A-to-partner and partner-to-KIF21A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF21A versus SSPN in HNSC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF21A→partner) and Y-score (partner→KIF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SSPN →	-0.951	-0.297	<.001	<.001	3	6
GBM	FCGR2A →	-0.728	-0.316	<.001	<.001	3	6
GBM	COLEC12 →	-0.950	-0.300	<.001	<.001	3	6
BRCA	FOLR2 →	-0.896	-0.193	<.001	.006	3	6
HNSC	MEF2C →	-0.632	-0.224	.001	.001	3	6
COAD	HSPA4L →	+0.876	+0.237	.004	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,056 associations by consensus.

KIF21A vs SSPN — HNSC

Explore this scatter interactively →