KIF21A

Across TCGA patient cohorts, KIF21A protein abundance is significantly associated with the protein abundance of many other proteins, with 19,610 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIF21A-associated proteins across cancer lineages are KIF21A_S1212, KIF21A_S1239, and ILK. Each is linked with KIF21A in more than 9 cancer types. Because this analysis shows association rather than direction, both KIF21A-to-partner and partner-to-KIF21A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF21A versus KIF21A_S1212 in LSCC, with a Pearson correlation of 0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF21A→partner) and Y-score (partner→KIF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KIF21A_S1212 →	+0.776	+0.621	<.001	<.001	3	10
OV	KIF21A_S1239 →	+1.024	+0.415	<.001	<.001	3	9
BRCA	ILK →	-0.352	-0.349	<.001	<.001	3	6
PDAC	HDAC7_S181 →	-0.638	-0.184	<.001	<.001	3	6
LSCC	CLPX →	+0.280	+0.413	<.001	<.001	3	6
GBM	COL6A2 →	-0.634	-0.313	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,610 associations by consensus.

KIF21A vs KIF21A_S1212 — LSCC

Explore this scatter interactively →