KIF21A

Across TCGA cell cohorts, KIF21A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,029 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KIF21A-associated GO terms across cancer lineages are Regulation of axon guidance, Anterograde axonal transport, and Regulation of microtubule depolymerization. Each is linked with KIF21A in more than 10 cancer types. Because this analysis shows association rather than direction, both KIF21A-to-partner and partner-to-KIF21A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of axon guidance grouped by KIF21A-low versus KIF21A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF21A→partner) and Y-score (partner→KIF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of axon guidance →	+0.259	+1.519	.002	.001	3	11
KIDNEY	Anterograde axonal transport →	+0.089	+0.781	<.001	.009	3	10
PANCREAS	Regulation of microtubule depolymerization →	+0.069	+0.819	<.001	.001	3	9
STOMACH	Negative regulation of gene expression, epigenetic →	+0.067	+1.000	.002	<.001	3	9
LARGE_INTESTINE	Protein-RNA complex assembly →	+0.049	+0.841	.002	.003	3	9
LARGE_INTESTINE	Protein-RNA complex organization →	+0.052	+0.753	<.001	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,029 associations by consensus.

Regulation of axon guidance by KIF21A expression — LIVER

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