KIF1B

Across TCGA patient cohorts, KIF1B mutation is significantly associated with the RNA expression of many other genes, with 8,565 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF1B-associated genes across cancer lineages are PSMD9, KIF22, and ENO2. Each is linked with KIF1B in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF1B-to-partner and partner-to-KIF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by KIF1B-low versus KIF1B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1B→partner) and Y-score (partner→KIF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PSMD9 →	+0.394	+2.512	<.001	<.001	3	6
UCEC	KIF22 →	+0.456	+1.818	<.001	<.001	3	5
STAD	ENO2 →	+0.875	+3.472	.001	.002	3	5
UCEC	PPP1R8 →	+0.416	+1.657	<.001	<.001	3	5
UCEC	PPAT →	+0.593	+1.378	<.001	<.001	3	5
STAD	RER1 →	+0.426	+3.334	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,565 associations by consensus.

PSMD9 by KIF1B expression — COAD

Explore this box plot interactively →