KIF1A

Across TCGA cell cohorts, KIF1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,691 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KIF1A-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, Epigenetic regulation of gene expression, and Protein-DNA complex organization. Each is linked with KIF1A in more than 11 cancer types. Because this analysis shows association rather than direction, both KIF1A-to-partner and partner-to-KIF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by KIF1A-low versus KIF1A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1A→partner) and Y-score (partner→KIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of double-strand break repair via homologous recombination →	+0.086	+2.138	<.001	<.001	3	12
STOMACH	Epigenetic regulation of gene expression →	+0.080	+2.337	.001	<.001	3	12
STOMACH	Protein-DNA complex organization →	+0.071	+2.343	<.001	.001	3	12
STOMACH	Anterograde neuronal dense core vesicle transport →	-0.246	-2.970	<.001	<.001	3	11
BONE	Cell cycle phase transition →	+0.096	+2.500	<.001	.001	3	11
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.152	+2.526	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by KIF1A expression — OVARY

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