KIF1A

Across TCGA cell cohorts, KIF1A mutation is significantly associated with the RNA expression of many other genes, with 375 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF1A-associated genes across cancer lineages are CSNKA2IP, RAB19, and R3HDM1. Each is linked with KIF1A in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF1A-to-partner and partner-to-KIF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSNKA2IP grouped by KIF1A-low versus KIF1A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF1A→partner) and Y-score (partner→KIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CSNKA2IP →	+0.079	+3.662	<.001	.002	3	3
LARGE_INTESTINE	RAB19 →	+0.710	+2.743	.003	.001	3	3
LARGE_INTESTINE	R3HDM1 →	+0.521	+3.321	.002	.003	3	3
BLOOD_Leukemia	PRR30 →	+0.018	+4.421	<.001	<.001	3	2
BLOOD_Leukemia	DPRX →	+0.089	+3.475	<.001	.001	3	2
LARGE_INTESTINE	HINT3 →	+0.648	+3.321	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 375 associations by consensus.

CSNKA2IP by KIF1A expression — BLOOD_Lymphoma

Explore this box plot interactively →