Across TCGA patient cohorts, KIF19 mutation is significantly associated with the RNA expression of many other genes, with 3,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF19-associated genes across cancer lineages are CHP1, UBR7, and PSMC3IP. Each is linked with KIF19 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF19-to-partner and partner-to-KIF19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF19→partner) and Y-score (partner→KIF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHP1 →	+0.488	+2.110	<.001	<.001	3	5
UCEC	UBR7 →	+0.434	+2.524	<.001	<.001	3	5
UCEC	PSMC3IP →	+0.634	+1.903	<.001	<.001	3	5
COAD	KIAA0895 →	+0.719	+3.820	<.001	<.001	3	5
UCEC	MYO19 →	+0.423	+2.728	<.001	<.001	3	4
UCEC	WDHD1 →	+0.497	+2.021	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,188 associations by consensus.

Exploration

KIF19 survival (RNA) · tumor vs normal (RNA) · all KIF19 data types