Across TCGA patient cohorts, KIF19 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. COAD shows the largest number of these associations.

The most reproducible KIF19-associated genes across cancer lineages are INPP4B, PKC-a, and XRCC1. Each is linked with KIF19 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF19-to-partner and partner-to-KIF19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF19→partner) and Y-score (partner→KIF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.512	-3.459	.001	.004	3	3
COAD	PKC-a →	-0.416	-2.321	<.001	.033	3	2
LUAD	XRCC1 →	+0.175	+3.459	.012	.005	3	2
UCEC	C-Raf →	+0.117	+2.070	.018	.001	3	2
COAD	Cyclin-B1 →	+0.564	+2.593	.013	.006	3	2
COAD	eIF4E →	+0.166	+3.012	.026	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

KIF19 survival (RNA) · tumor vs normal (RNA) · all KIF19 data types