Across TCGA cell cohorts, KIF19 mutation is significantly associated with the RNA expression of many other genes, with 435 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF19-associated genes across cancer lineages are PBOV1, XIRP1, and OR6M1. Each is linked with KIF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF19-to-partner and partner-to-KIF19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF19→partner) and Y-score (partner→KIF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PBOV1 →	+0.016	+4.196	<.001	.002	3	2
LUNG_NSCLC_LUAD	XIRP1 →	+0.023	+3.876	<.001	.003	3	2
BLOOD_Leukemia	OR6M1 →	+0.019	+4.124	<.001	<.001	3	2
SOFT_TISSUE	PGK2 →	+0.159	+5.515	<.001	<.001	3	1
SOFT_TISSUE	OR4X2 →	+0.024	+4.369	<.001	.008	3	1
SKIN	DAZ3 →	+0.597	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 435 associations by consensus.

Exploration

KIF19 survival (RNA) · tumor vs normal (RNA) · all KIF19 data types