Across TCGA cell cohorts, KIF19 mutation is significantly associated with the mutation status of many other genes, with 3,609 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF19-associated genes across cancer lineages are RYR3, IGSF9B, and CRAMP1. Each is linked with KIF19 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF19-to-partner and partner-to-KIF19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF19→partner) and Y-score (partner→KIF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RYR3 →	+2.552	+4.157	.003	.003	1	6
SOFT_TISSUE	IGSF9B →	+2.985	+3.562	.008	.008	1	6
CNS	CRAMP1 →	+4.614	+4.614	.006	.006	1	5
BLOOD_Leukemia	RNF213 →	+1.570	+2.376	.005	.005	1	5
SOFT_TISSUE	CNTNAP2 →	+4.307	+4.307	.001	.001	1	5
LARGE_INTESTINE	RP1 →	+1.445	+2.169	.006	.006	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,609 associations by consensus.

Exploration

KIF19 survival (RNA) · tumor vs normal (RNA) · all KIF19 data types