KIF18BP1

Across TCGA pan-cancer cohorts, KIF18BP1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated KIF18BP1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher KIF18BP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIF18BP1 expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

UVM, TGCT, and THYM are the cancer types where KIF18BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.528	0.863	.006	72	view →
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	36	view →
THYM	OS	Tertile	All	0.778	0.983	.002	36	view →
DLBC	OS	Tertile	All	0.526	0.936	.002	24	view →
LIHC	DFS	Tertile	All	0.306	0.562	.020	18	view →
LUSC	DFS	Quartile	III,IV	0.148	0.628	.014	17	view →
PCPG	DFS	Tertile	All	0.740	0.955	.002	15	view →
LUAD	OS	Tertile	II,III,IV	0.316	0.478	.046	6	view →
MESO	OS	Quartile	All	0.548	0.341	.028	3	view →
SKCM	DFS	Quartile	All	0.685	0.773	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

KIF18BP1–UVM (OS)

Open the UVM breakdown →