KIF18A

Across TCGA patient cohorts, KIF18A protein abundance is significantly associated with the protein abundance of many other proteins, with 18,000 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF18A-associated proteins across cancer lineages are TPR_S1185, RANBP2_S3207, and CRAMP1_S596. Each is linked with KIF18A in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF18A-to-partner and partner-to-KIF18A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF18A versus TPR_S1185 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF18A→partner) and Y-score (partner→KIF18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TPR_S1185 →	+1.364	+0.682	.002	.002	2	4
LSCC	RANBP2_S3207 →	+0.883	+0.820	<.001	.001	3	3
GBM	CRAMP1_S596 →	+1.385	+1.623	<.001	.001	3	2
LSCC	DDI2_S128 →	+0.980	+1.376	<.001	.002	3	2
GBM	DST_S2529 →	-1.591	-1.512	<.001	<.001	3	2
GBM	ENTR1_S243 →	-1.312	-1.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,000 associations by consensus.

KIF18A vs TPR_S1185 — BRCA

Explore this scatter interactively →