KIF16B

Across TCGA patient cohorts, KIF16B mutation is significantly associated with the RNA expression of many other genes, with 8,058 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF16B-associated genes across cancer lineages are ABHD17C, MRPS22, and MRPL19. Each is linked with KIF16B in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF16B-to-partner and partner-to-KIF16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD17C grouped by KIF16B-low versus KIF16B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF16B→partner) and Y-score (partner→KIF16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ABHD17C →	+0.913	+3.945	<.001	<.001	3	5
SKCM	MRPS22 →	+0.471	+2.398	<.001	<.001	3	5
UCEC	MRPL19 →	+0.516	+1.657	<.001	<.001	3	5
COAD	RNA5SP477 →	+1.054	+2.752	<.001	<.001	3	4
COAD	TXN2 →	+0.406	+3.362	.002	.004	3	4
UCEC	OIP5 →	+0.851	+2.545	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,058 associations by consensus.

ABHD17C by KIF16B expression — SKCM

Explore this box plot interactively →