KIF16B

Across TCGA patient cohorts, KIF16B mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF16B-associated genes across cancer lineages are eIF4E, ATM, and eEF2. Each is linked with KIF16B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF16B-to-partner and partner-to-KIF16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by KIF16B-low versus KIF16B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF16B→partner) and Y-score (partner→KIF16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.240	+3.025	.009	.019	3	3
UCEC	ATM →	-0.609	-1.874	<.001	<.001	3	3
SKCM	eEF2 →	+0.365	+3.321	.016	.009	3	3
UCEC	Ku80 →	+0.210	+1.335	.001	.003	3	3
UCEC	PCNA →	+0.218	+2.321	<.001	<.001	3	3
UCEC	Bap1-c-4 →	+0.129	+1.267	.034	.026	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

eIF4E by KIF16B expression — COAD

Explore this box plot interactively →