KIF16B

Across TCGA cell cohorts, KIF16B mutation is significantly associated with the RNA expression of many other genes, with 809 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF16B-associated genes across cancer lineages are RXFP2, RBMXL2, and LIG4. Each is linked with KIF16B in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF16B-to-partner and partner-to-KIF16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RXFP2 grouped by KIF16B-low versus KIF16B-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF16B→partner) and Y-score (partner→KIF16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RXFP2 →	+0.256	+4.228	<.001	.006	3	2
LARGE_INTESTINE	RBMXL2 →	+0.070	+2.632	<.001	.008	3	2
LARGE_INTESTINE	LIG4 →	+0.621	+3.389	<.001	.001	3	2
LARGE_INTESTINE	HACE1 →	+0.896	+2.386	<.001	.007	3	2
OESOPHAGUS	OR1L4 →	+0.032	+3.392	<.001	.007	3	1
OESOPHAGUS	OR5C1 →	+0.067	+3.836	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 809 associations by consensus.

RXFP2 by KIF16B expression — OVARY

Explore this box plot interactively →