Across TCGA pan-cancer cohorts, KIF13B RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of KIF13B’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KIF13B RNA is repressed in tumor relative to normal tissue. In most cancer types KIF13B is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.
KIRC, COAD, and HNSC are the cancer types where KIF13B tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF13B RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.