KIF11

Across TCGA patient cohorts, KIF11 protein abundance is significantly associated with the RNA expression of many other genes, with 22,257 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF11-associated genes across cancer lineages are CDKN3, MYBL2, and E2F1. Each is linked with KIF11 in more than 7 cancer types. Because this analysis shows association rather than direction, both KIF11-to-partner and partner-to-KIF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF11 versus CDKN3 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF11→partner) and Y-score (partner→KIF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN3 →	+1.327	+0.656	<.001	<.001	3	8
BRCA	MYBL2 →	+1.582	+0.648	<.001	<.001	3	8
BRCA	E2F1 →	+1.219	+0.648	<.001	<.001	3	8
BRCA	FAM83D →	+1.356	+0.848	<.001	<.001	3	8
BRCA	CENPI →	+1.032	+0.846	<.001	<.001	3	8
BRCA	NEIL3 →	+1.025	+0.806	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,257 associations by consensus.

KIF11 vs CDKN3 — OV

Explore this scatter interactively →