KIF11

Across TCGA patient cohorts, KIF11 mutation is significantly associated with the RNA expression of many other genes, with 1,793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF11-associated genes across cancer lineages are RNA5SP432, H3P42, and PPIAP88. Each is linked with KIF11 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF11-to-partner and partner-to-KIF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP432 grouped by KIF11-low versus KIF11-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF11→partner) and Y-score (partner→KIF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP432 →	+0.389	+4.978	<.001	.005	3	3
SKCM	H3P42 →	+0.134	+4.470	<.001	.005	3	2
BLCA	PPIAP88 →	+0.093	+4.719	.002	.003	3	2
CESC	EEF1E1-BLOC1S5 →	+0.033	+4.384	<.001	.008	3	2
CESC	NF1P10 →	+0.289	+4.984	<.001	.003	3	2
UCEC	IGHD2-15 →	+0.933	+1.397	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,793 associations by consensus.

RNA5SP432 by KIF11 expression — LUSC

Explore this box plot interactively →