KIAA2013

Across TCGA pan-cancer cohorts, KIAA2013 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KIAA2013’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where KIAA2013 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types KIAA2013 is over-expressed in tumor, although a few such as COAD and PDAC show the opposite, repressed pattern.

COAD, PDAC, and LUAD are the cancer types where KIAA2013 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA2013 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.110	<.001	6	view →
PDAC	Female	All	−0.399	<.001	4	view →
LUAD	Male	All	−0.143	<.001	4	view →
HNSC	All	IV	+0.218	.015	2	view →
LSCC	All	All	+0.088	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

KIAA2013–COAD

Open the COAD breakdown →