KIAA1958

Across TCGA pan-cancer cohorts, KIAA1958 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIAA1958 data layer compared with 25 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KIAA1958 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA1958 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

OV, HNSC, and UCEC are the cancer types where KIAA1958 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.366	0.692	.011	36	view →
HNSC	OS	Median	III,IV	0.115	0.746	<.001	24	view →
UCEC	DFS	Median	All	0.962	0.625	.016	14	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
ACC	OS	Median	All	0.149	0.686	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIAA1958–OV (OS)

Open the OV breakdown →