KIAA1958

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KIAA1958 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KIAA1958 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KIAA1958 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIAA1958 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where KIAA1958 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.3451.000.00514view →
LSCCDFSQuartileAll0.6630.952.0127view →
UCECDFSMedianAll1.0000.716.0104view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KIAA1958–LUAD (DFS)

Kaplan–Meier survival curve for KIAA1958 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration