KIAA1958

Across TCGA patient cohorts, KIAA1958 mutation is significantly associated with the RNA expression of many other genes, with 4,583 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1958-associated genes across cancer lineages are PSMD11, MCMBP, and CEP78. Each is linked with KIAA1958 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1958-to-partner and partner-to-KIAA1958 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD11 grouped by KIAA1958-low versus KIAA1958-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1958→partner) and Y-score (partner→KIAA1958) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMD11 →	+0.487	+3.080	<.001	<.001	3	4
UCEC	MCMBP →	+0.479	+2.255	<.001	<.001	3	4
UCEC	CEP78 →	+0.666	+3.700	<.001	<.001	3	4
SKCM	REXO5 →	+0.562	+3.195	.001	.009	3	4
CESC	NCOA4P1 →	+0.028	+3.705	<.001	.008	3	3
UCEC	CRYBB2P1 →	+0.385	+2.223	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,583 associations by consensus.

PSMD11 by KIAA1958 expression — UCEC

Explore this box plot interactively →