KIAA1958

Across TCGA patient cohorts, KIAA1958 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1958-associated genes across cancer lineages are ATM, PCNA, and eIF4E. Each is linked with KIAA1958 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1958-to-partner and partner-to-KIAA1958 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KIAA1958-low versus KIAA1958-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1958→partner) and Y-score (partner→KIAA1958) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.517	-2.070	<.001	.001	3	4
LUSC	PCNA →	+0.256	+2.816	.029	.036	3	3
UCEC	eIF4E →	+0.164	+3.183	.025	.009	3	3
UCEC	Caspase-7-cleavedD198 →	+0.606	+3.019	.003	<.001	3	3
UCEC	Cyclin-B1 →	+0.752	+3.807	<.001	<.001	3	3
UCEC	EGFR_pY1068 →	-0.226	-2.000	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ATM by KIAA1958 expression — UCEC

Explore this box plot interactively →