KIAA1958

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KIAA1958 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KIAA1958-associated genes across cancer lineages are CCER1, AADACL2, and KRTAP10-6. Each is linked with KIAA1958 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1958-to-partner and partner-to-KIAA1958 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCER1 grouped by KIAA1958-low versus KIAA1958-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1958→partner) and Y-score (partner→KIAA1958) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSCCER1 →+0.016+5.754<.001.00232
BLOOD_LymphomaAADACL2 →+0.008+3.925<.001.00631
LARGE_INTESTINEKRTAP10-6 →+0.055+4.347<.001.00131
STOMACHMSGN1 →+0.115+4.285<.001.00731
OVARYIL22 →+0.064+4.029<.001.00931
OVARYTAAR1 →+0.038+4.029.002.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

CCER1 by KIAA1958 expression — CNS

Box plot of CCER1 in KIAA1958-low vs KIAA1958-high samples in CNS.

Explore this box plot interactively →

Exploration