KIAA1841

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KIAA1841 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KIAA1841 data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher KIAA1841 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIAA1841 expression acts as an unfavorable survival marker.

SKCM, BLCA, and UCEC are the cancer types where KIAA1841 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSMedianAll0.1520.764<.00115view →
BLCAOSMedianIV0.1410.589.0186view →
UCECOSMedianIV0.2310.592.0366view →
LIHCDFSMedianAll0.1460.555.0403view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KIAA1841–SKCM (DFS)

Kaplan–Meier survival curve for KIAA1841 mutant vs wild-type samples in SKCM.

Open the SKCM breakdown →

Exploration