KIAA1755

Across TCGA pan-cancer cohorts, KIAA1755 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KIAA1755 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KIAA1755 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KIAA1755 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

KIRP, UCEC, and LUAD are the cancer types where KIAA1755 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.440	0.887	<.001	42	view →
UCEC	OS	Median	II,III,IV	0.953	0.445	.003	34	view →
LUAD	OS	Median	III,IV	0.359	0.685	.006	14	view →
SKCM	DFS	Median	II,III,IV	0.983	0.660	.010	4	view →
LGG	DFS	Median	All	0.201	0.728	.011	3	view →
SCLC	OS	Median	II,III,IV	1.000	0.395	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KIAA1755–KIRP (OS)

Open the KIRP breakdown →