KIAA1755

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIAA1755 mutation is significantly associated with the RNA expression of many other genes, with 7,481 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1755-associated genes across cancer lineages are EHMT1, PRC1, and DDX11-AS1. Each is linked with KIAA1755 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1755-to-partner and partner-to-KIAA1755 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EHMT1 grouped by KIAA1755-low versus KIAA1755-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1755→partner) and Y-score (partner→KIAA1755) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEHMT1 →+0.409+1.954<.001<.00134
LUADPRC1 →+0.764+1.938<.001.00134
LUADDDX11-AS1 →+0.437+2.915<.001<.00134
LUSCTRAM2-AS1 →+0.432+2.906.008.00134
UCECOIP5 →+0.729+2.310<.001<.00134
COADPSMD9 →+0.335+2.753<.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,481 associations by consensus.

EHMT1 by KIAA1755 expression — UCEC

Box plot of EHMT1 in KIAA1755-low vs KIAA1755-high samples in UCEC.

Explore this box plot interactively →

Exploration