KIAA1755

Across TCGA patient cohorts, KIAA1755 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA1755-associated genes across cancer lineages are Caspase-7-cleavedD198, Ku80, and Claudin-7. Each is linked with KIAA1755 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA1755-to-partner and partner-to-KIAA1755 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by KIAA1755-low versus KIAA1755-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1755→partner) and Y-score (partner→KIAA1755) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.995	+2.186	.001	.032	3	4
UCEC	Ku80 →	+0.230	+2.335	<.001	<.001	3	3
LUAD	Claudin-7 →	+0.642	+2.087	.002	.005	3	3
UCEC	Cyclin-B1 →	+0.445	+2.502	.003	.001	3	3
LUAD	EGFR →	-0.233	-3.169	.012	.018	3	2
LUAD	G6PD →	-0.364	-3.169	.029	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Caspase-7-cleavedD198 by KIAA1755 expression — COAD

Explore this box plot interactively →