KIAA1755

Across TCGA cell cohorts, KIAA1755 mutation is significantly associated with the mutation status of many other genes, with 6,200 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1755-associated genes across cancer lineages are MUC3A, SACS, and SDK2. Each is linked with KIAA1755 in more than 6 cancer types. Because this analysis shows association rather than direction, both KIAA1755-to-partner and partner-to-KIAA1755 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MUC3A grouped by KIAA1755-low versus KIAA1755-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1755→partner) and Y-score (partner→KIAA1755) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MUC3A →	+2.662	+2.000	.008	.008	1	7
SOFT_TISSUE	SACS →	+2.630	+3.447	.004	.004	1	6
SOFT_TISSUE	SDK2 →	+4.022	+3.722	.003	.003	1	5
CNS	BMPER →	+4.584	+4.277	.001	.001	1	5
CNS	LIG4 →	+5.000	+4.044	.008	.008	1	5
SOFT_TISSUE	CACNA1I →	+4.022	+3.722	.003	.003	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,200 associations by consensus.

MUC3A by KIAA1755 expression — LARGE_INTESTINE

Explore this box plot interactively →