KIAA1614

Across TCGA cell cohorts, KIAA1614 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA1614-associated genes across cancer lineages are SFT2D3, TBC1D28, and DBX2. Each is linked with KIAA1614 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA1614-to-partner and partner-to-KIAA1614 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFT2D3 grouped by KIAA1614-low versus KIAA1614-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA1614→partner) and Y-score (partner→KIAA1614) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SFT2D3 →	+0.445	+3.772	<.001	<.001	3	2
BLOOD_Leukemia	TBC1D28 →	+0.087	+4.189	<.001	<.001	3	2
PANCREAS	DBX2 →	+0.006	+5.000	<.001	.006	3	1
LUNG_NSCLC_LUAD	CLEC4C →	+0.029	+3.362	<.001	.007	3	1
LARGE_INTESTINE	CCDC134 →	+0.819	+3.131	.002	.008	3	1
OVARY	MLN →	+0.667	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

SFT2D3 by KIAA1614 expression — BLOOD_Leukemia

Explore this box plot interactively →