KIAA1522

Across TCGA pan-cancer cohorts, KIAA1522 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIAA1522 data layer compared with 17 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KIAA1522 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KIAA1522 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, UCEC, and PDAC are the cancer types where KIAA1522 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	1.000	0.835	.032	42	view →
UCEC	DFS	Tertile	II,III,IV	1.000	0.492	.008	24	view →
PDAC	OS	Quartile	III,IV	0.641	1.000	.022	5	view →
LUAD	OS	Tertile	All	1.000	0.965	.022	4	view →
CCRCC	DFS	Tertile	All	0.985	0.531	.009	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIAA1522–COAD (DFS)

Open the COAD breakdown →