KIAA1328

Across TCGA pan-cancer cohorts, KIAA1328 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KIAA1328’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where KIAA1328 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types KIAA1328 is over-expressed in tumor, although a few such as LSCC and HNSC show the opposite, repressed pattern.

LSCC, HNSC, and PDAC are the cancer types where KIAA1328 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA1328 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Female	All	−0.558	<.001	7	view →
HNSC	Male	All	−0.458	.027	2	view →
PDAC	Male	III,IV	−0.363	.033	1	view →
LUAD	Male	III,IV	−0.238	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

KIAA1328–LSCC

Open the LSCC breakdown →